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Reversine

Reversine

Item no.	V0351-50mg
Manufacturer	InvivoChem LLC
CASRN	656820-32-5
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0351CAS #:656820-32-5Purity >=98% Description: Reversine is a cell-permeable, selective and ATP-competitive inhibitor of human A3 adenosine receptor and a pan-aurora A/B/C kinase inhibitor as well with potential anticancer activity. It inhibits human A3 adenosine receptor with a Ki of 0.66 uM, and inhibits pan-aurora A/B/C kinase with IC50s of 12 nM/13 nM/20 nM, respectively. It shows potent in vitro antiproliferative activity and high in vivo antitumor efficacy. Description: References: J Am Chem Soc. 2004; 126(2):410-1; Mol Cancer Ther. 2008; 7(5):1140-9; Cytotechnology. 2013; 65(4):643-53. References:
Molecular Weight (MW)	393.23
Formula	C21H27N7O
CAS No.	656820-32-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 5 mg/mL (12.7 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: N6-cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2, 6-diamine InChi Key: ZFLJHSQHILSNCM-UHFFFAOYSA-N InChi Code: InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9, 14-15H, 1-5, 10-13H2, (H3, 22, 23, 24, 25, 26, 27) SMILES Code: C12=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC(NC5CCCCC5)=C1NC=N2
Synonyms	Reversine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 9/4/2025

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