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TAK-901

TAK-901

Item no.	V0362-100mg
Manufacturer	InvivoChem LLC
CASRN	934541-31-8
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0362CAS #: 934541-31-8Purity >=98% Description: TAK-901 (TAK901) is a novel and potent inhibitor of Aurora A/B kinases with potential antitumor activity. It inhibits Aurora A/B with IC50s of 21 nM and 15 nM, respectively, and shows little/no activity against JAK2, c-Src or Abl. TAK-901 displayed potent in vitro antiproliferative activity and high in vivo antitumor efficacy by binding to and inhibiting the activity of Aurora B, leading to a decrease in the proliferation of tumor cells that overexpress Aurora B. Description: References: Mol Cancer Ther. 2013 Apr; 12(4):460-70. References:
Molecular Weight (MW)	504.64
Formula	C28H32N4O3S
CAS No.	934541-31-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 101 mg/mL (200.1 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 5-(3-(ethylsulfonyl)phenyl)-3, 8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2, 3-b]indole-7-carboxamide InChi Key: WKDACQVEJIVHMZ-UHFFFAOYSA-N InChi Code: InChI=1S/C28H32N4O3S/c1-5-36(34, 35)21-8-6-7-19(14-21)23-15-22(28(33)30-20-9-11-32(4)12-10-20)18(3)26-25(23)24-13-17(2)16-29-27(24)31-26/h6-8, 13-16, 20H, 5, 9-12H2, 1-4H3, (H, 29, 31)(H, 30, 33) SMILES Code: O=C(C1=C(C)C2=C(C(C3=CC=CC(S(=O)(CC)=O)=C3)=C1)C4=CC(C)=CN=C4N2)NC5CCN(C)CC5
Synonyms	TAK-901, TAK 901, TAK901

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Amount: 100 mg

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Delivery expected until 10/2/2025

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