MI-3

Item no.	V0398-500mg
Manufacturer	InvivoChem LLC
CASRN	1271738-59-0
Amount	500 mg
Quantity options	100 mg 10 mg 1 mg 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0398CAS #:1271738-59-0Purity >=98% Description: MI-3 (Menin-MLL Inhibitor 3) is a novel and potent inhibitor of menin-MLL interaction with potential antitumor activity. It inhibits menin-MLL interaction with an IC50 of 648 nM. It exhibits excellent antiproliferative activity against various cancer cells. Description: References: Nat Chem Biol. 2012 Jan 29; 8(3):277-84. References:
Molecular Weight (MW)	375.55
Formula	C18H25N5S2
CAS No.	1271738-59-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 19 mg/mL (50.6 mM)
	Water:< 1 mg/mL
	Ethanol: 19 mg/mL (50.6 mM)
Other info	Chemical Name: 4-[4-(5, 5-dimethyl-4H-1, 3-thiazol-2-yl)piperazin-1-yl]-6-propan-2-ylthieno[2, 3-d]pyrimidine InChi Key: FUGQNAUKABUDQI-UHFFFAOYSA-N InChi Code: InChI=1S/C18H25N5S2/c1-12(2)14-9-13-15(20-11-21-16(13)24-14)22-5-7-23(8-6-22)17-19-10-18(3, 4)25-17/h9, 11-12H, 5-8, 10H2, 1-4H3 SMILES Code: CC(C1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1)C
Synonyms	MI 3; MI-3; MI3

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Amount: 500 mg

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