Comparison

MI-3

Item no. V0398-50mg
Manufacturer InvivoChem LLC
CASRN 1271738-59-0
Amount 50 mg
Quantity options 100 mg 10 mg 1 mg 250 mg 25 mg 500 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0398CAS #:1271738-59-0Purity >=98%

Description: MI-3 (Menin-MLL Inhibitor 3) is a novel and potent inhibitor of menin-MLL interaction with potential antitumor activity. It inhibits menin-MLL interaction with an IC50 of 648 nM. It exhibits excellent antiproliferative activity against various cancer cells.

Description:

References: Nat Chem Biol. 2012 Jan 29; 8(3):277-84.

References:
Molecular Weight (MW)
375.55
Formula
C18H25N5S2
CAS No.
1271738-59-0
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 19 mg/mL (50.6 mM)
Water:< 1 mg/mL
Ethanol: 19 mg/mL (50.6 mM)
Other info

Chemical Name: 4-[4-(5, 5-dimethyl-4H-1, 3-thiazol-2-yl)piperazin-1-yl]-6-propan-2-ylthieno[2, 3-d]pyrimidine

InChi Key: FUGQNAUKABUDQI-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H25N5S2/c1-12(2)14-9-13-15(20-11-21-16(13)24-14)22-5-7-23(8-6-22)17-19-10-18(3, 4)25-17/h9, 11-12H, 5-8, 10H2, 1-4H3

SMILES Code: CC(C1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1)C

Synonyms
MI 3; MI-3; MI3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
available

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