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SCH772984

SCH772984

Item no.	V0463-500mg
Manufacturer	InvivoChem LLC
CASRN	942183-80-4
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0463CAS #:942183-80-4Purity >=98% Description: SCH772984 (SCH-772984) is a novel, potent and ATP-competitive inhibitor of ERK1/2 with potential antitumor activity. It inhibits ERK1/2 with IC50s of 4 nM and 1 nM in cell-free assay, respectively. SCH772984 was identified by an affinity-based mass spectroscopy high-throughput platform with potential anticancer activity. SCH772984 is highly selective against kinases such as CLK2, FLT4, GSG2, MAP4K4, MAPK1, MINK1, PRKD1 and TTK, out of a wide range of 300 tested with more than 50% inhibition at a concentration of 1 umol/L. Description: References: Cancer Discov. 2013 Jul; 3(7):742-50. References:
Molecular Weight (MW)	587.67
Formula	C33H33N9O2
CAS No.	942183-80-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 0.1 mg/mL (0.17 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	5% DMSO+30% PEG 300+ddH2O: 0.6 mg/mL
Synonyms	SCH-772984; SCH 772984; SCH772984; (R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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