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BMS-794833

BMS-794833

Item no.	V0501-250mg
Manufacturer	InvivoChem LLC
CASRN	1174046-72-0
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Neuroscience Aging & Neurological Disorders Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0501CAS #:1174046-72-0Purity >=98% Description: BMS-794833 (BMS794833; BMS 794833) is an ATP competitive multi-kinase (Met/VEGFR2) inhibitor with potential anticancer activity. It inhibits Met/VEGFR2 with IC50s of 1.7 nM and 15 nM, respectively. BMS-794833 demonstrates high anti-proliferative activity in vitro and in vivo antitumor efficacy in a human gastric tumor xenografts model and a U87 glioblastoma model. Description: human gastric tumor xenografts model and a U87 glioblastoma model. References: WO2009094417A1 References:
Molecular Weight (MW)	468.84
Formula	C23H15ClF2N4O3
CAS No.	1174046-72-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 94 mg/mL (200.5 mM)
	Water:< 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES	O=C(C1=CNC=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C(Cl)C(N)=NC=C4)C(F)=C3
Synonyms	BMS-794833; BMS 794833; BMS794833; N-(4-((2-amino-3-chloropyridin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-4-oxo-1, 4-dihydropyridine-3-carboxamide InChi Key: PDYXPCKITKHFOZ-UHFFFAOYSA-N InChi Code: InChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H, (H2, 27, 29)(H, 28, 31)(H, 30, 32) SMILES Code: O=C(C1=CNC=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C(Cl)C(N)=NC=C4)C(F)=C3

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Amount: 250 mg

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Delivery expected until 10/2/2025

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