Comparison

NVP-BVU972

Item no. V0597-10mg
Manufacturer InvivoChem LLC
CASRN 1185763-69-2
Amount 10 mg
Quantity options 100 mg 1 mg 250 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0597CAS #:1185763-69-2Purity >=98%

Description: NVP-BVU972 (also names as BVN972; BVN-972) is a novel c-Met inhibitor with potential anticancer activity. It inhibits c-Met with an IC50 of 14 nM. It exhibits excellent anti-proliferative activity in vitro against various cancer cells such as EBC-1, GTL-16, and MKN-45 with IC50 values of 82, 66 and 32 nM, respectively.

Description:

References: Cancer Res. 2011 Aug 1; 71(15):5255-64.

References:
Molecular Weight (MW)
340.38
Formula
C20H16N6
CAS No.
1185763-69-2
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 68 mg/mL (199.8 mM)
Water: < 1 mg/mL
Ethanol: 68 mg/mL (199.8 mM)
Other info
Chemical Name: 6-[[6-(1-methylpyrazol-4-yl)imidazo[1, 2-b]pyridazin-3-yl]methyl]quinoline
InChi Key: RNCNPRCUHHDYPC-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H16N6/c1-25-13-16(11-23-25)19-6-7-20-22-12-17(26(20)24-19)10-14-4-5-18-15(9-14)3-2-8-21-18/h2-9, 11-13H, 10H2, 1H3
SMILES Code: CN1N=CC(C2=NN3C(C=C2)=NC=C3CC4=CC=C5N=CC=CC5=C4)=C1
Synonyms
NVP-BVU-972; BVU-972; NVP-BVU972; NVP-BVU 972; BVU 972; BVU972.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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