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SSR128129E (SSR 128129E; SSR128129 E)

SSR128129E (SSR 128129E; SSR128129 E)

Item no.	V0620-10mg
Manufacturer	InvivoChem LLC
CASRN	848318-25-2
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0620CAS #:848318-25-2Purity >=98% Description: SSR128129E (also known as SSR-128129E; SSR 128129 E) is a novel, potent, orally bioavailable and allosteric FGFR1 inhibitor with potential anticancer and anti-inflammatory activity. It inhibits FGFR1 with IC50 of 1.9 uM, while it does not affect other related RTKs. It shows high in vivo efficacy in mouse model of arthritic and mousetumor model bearing pancreatic tumor cell line Panc02, murine mammarycarcinoma cell line 4T1, murine colon cancer cell line CT26, or humanbreast MCF7/ADR cell line. Description: ouse model of arthritic and mousetumor model bearing pancreatic tumor cell line Panc02, murine mammarycarcinoma cell line 4T1, murine colon cancer cell line CT26, or humanbreast MCF7/ADR cell line. References: Cancer Cell. 2013 Apr 15; 23(4):477-88; PLoS One. 2013 Nov 4; 8(11):e80027. References: Related CAS: 848318-25-2 (sodium); 848463-13-8 (free)
Molecular Weight (MW)	346.31
Formula	C18H15N2O4.Na
CAS No.	848318-25-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 69 mg/mL (199.2 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: sodium 2-amino-5-(1-methoxy-2-methylindolizine-3-carbonyl)benzoate InChi Key: JFBMSTWZURKQOC-UHFFFAOYSA-M InChi Code: InChI=1S/C18H16N2O4.Na/c1-10-15(20-8-4-3-5-14(20)17(10)24-2)16(21)11-6-7-13(19)12(9-11)18(22)23; /h3-9H, 19H2, 1-2H3, (H, 22, 23); /q; +1/p-1 SMILES Code: O=C([O-])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N.[Na+]
Synonyms	SSR 128129E; SSR-128129E; SSR128129E;

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Amount: 10 mg

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Delivery expected until 10/2/2025

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