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NVP-ADW742

NVP-ADW742

Item no.	V0624-500mg
Manufacturer	InvivoChem LLC
CASRN	475488-23-4
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Molecular Targets for Neuroscience Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0624CAS #:475488-23-4Purity >=98% Description: NVP-ADW742 (also known as ADW-742; ADW 742; GSK552602A; GSK-552602A) is a novel, potent and selective IGF-1R inhibitor with potential antitumor activity. It inhibits IGF-1R with an IC50 of 0.17 uM. It exhibits excellent in vivo antitumor efficacy in male SCID/NOD mice injected with MM-1S-Luc+ human MM cells. Description: ale SCID/NOD mice injected with MM-1S-Luc+ human MM cells References: Cancer Cell. 2004 Mar; 5(3):221-30. References:
Molecular Weight (MW)	453.58
Formula	C28H31N5O
CAS No.	475488-23-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mg/mL (22.0 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL (6.6 mM)
Solubility (In vivo)	NC1=C2C(N([CH]3C[CH](CN4CCCC4)C3)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1
Synonyms	GSK 552602A, ADW742; NVP-ADW742; NVP ADW-742; NVP ADW 742; ADW 742; ADW-742; GSK-552602A; GSK552602A; 5-(3-(benzyloxy)phenyl)-7-((1r, 3r)-3-(pyrrolidin-1-ylmethyl)cyclobutyl)-7H-pyrrolo[2, 3-d]pyrimidin-4-amine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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