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UNC2250

UNC2250

Item no.	V0636-100mg
Manufacturer	InvivoChem LLC
CASRN	1493694-70-4
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Cardiovascular Research Ischemia & Reperfusion Injury Hypertension Reagents & Chemicals Arrhythmias Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0636CAS #:1493694-70-4Purity >=98% Description: UNC2250 (UNC-2250) is a novel, potent and selective Mer inhibitor with potential antitumor activity. It inhibits Mer with an IC50 of 1.7 nM, and shows about 160- and 60-fold higher selectivity for inhibiting Mer over other closely related kinases such as Axl/Tyro3. UNC2250 demonstrates high anti-proliferative activity in vitro and in vivo antitumor efficacy as well. Description: References: J Med Chem. 2013 Dec 12; 56(23):9683-92. References:
Molecular Weight (MW)	440.58
Formula	C24H36N6O2
CAS No.	1493694-70-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 2 mg/mL (4.5 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (1r, 4r)-4-((2-(butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol InChi Key: HSYSSKFCQHXOBP-MXVIHJGJSA-N InChi Code: InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4, 9, 15-16, 19-20, 31H, 2-3, 5-8, 10-14, 17H2, 1H3, (H2, 25, 27, 28, 29)/t19-, 20- SMILES Code: O[CH]1CC[CH](NC2=NC(NCCCC)=NC=C2C3=NC=C(CN4CCOCC4)C=C3)CC1
Synonyms	UNC-2250, UNC 2250, UNC2250,

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 10/2/2025

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