ANA-12

Item no.	V0642-500mg
Manufacturer	InvivoChem LLC
CASRN	219766-25-3
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category	Metabolism Diabetes Obesity Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0642CAS #:219766-25-3Purity >=98% Description: ANA-12 (ANA12) is a novel, potent and selective TrkB inhibitor/antagonist with important biological activity. It inhibits the high and low affinity sites of TrkB with a Kd of 10 nM and 12 uM, respectively. Description: References: J Clin Invest. 2011 May 2; 121(5): 1846–1857; Eur J Neurosci. 2014 May; 39(9):1439-54. References:
Molecular Weight (MW)	407.49
Formula	C22H21N3O3S
CAS No.	219766-25-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 37 mg/mL (90.79 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: N-(2-((2-oxoazepan-3-yl)carbamoyl)phenyl)benzo[b]thiophene-2-carboxamide InChi Key: TUSCYCAIGRVBMD-UHFFFAOYSA-N InChi Code: InChI=1S/C22H21N3O3S/c26-20(25-17-10-5-6-12-23-21(17)27)15-8-2-3-9-16(15)24-22(28)19-13-14-7-1-4-11-18(14)29-19/h1-4, 7-9, 11, 13, 17H, 5-6, 10, 12H2, (H, 23, 27)(H, 24, 28)(H, 25, 26) SMILES Code: O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O
Synonyms	ANA 12; ANA-12; ANA12;

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Amount: 500 mg

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