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PI-1840

PI-1840

Item no.	V0694-100mg
Manufacturer	InvivoChem LLC
CASRN	1401223-22-0
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0694CAS #:1401223-22-0Purity >=98% Description: PI-1840 (PI1840; PI 1840) is a reversible/non-covalent and selective inhibitor of chymotrypsin-like (CT-L) activity of proteasome with potential anticancer activity. It inhibits chymotrypsin-like activity of proteasome with IC50 of 27 nM. PI-1840 exhibited excellent antitumor activity in nude mice of human breast tumor xenografts References: J Med Chem. 2013 May 23; 56(10):3783-805; J Biol Chem. 2014 Apr 25; 289(17):11906-15.
Molecular Weight (MW)	394.47
Formula	C22H26N4O3
CAS No.	1401223-22-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 78 mg/mL (197.7 mM)
	Water: < 1 mg/mL
	Ethanol: 33 mg/mL (83.7 mM)
SMILES	O=C(N(C(C)C)CC1=NC(C2=CC=CN=C2)=NO1)COC3=CC=C(CCC)C=C3
Synonyms	PI1840; PI 1840; PI-1840;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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