Comparison

WS6

Item no. V0759-50mg
Manufacturer InvivoChem LLC
CASRN 1421227-53-3
Amount 50 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0759CAS #:1421227-53-3Purity >=98%

Description: WS6 (WS6; WS 6) is a novel and potent small molecule modulator of beta cell proliferation via modulation of Erb3 binding protein-1 (EBP1) and the IkappaB kinase pathway with important biological activity. WS6 is able to ameliorate diabetes, and induce concomitant increases in beta cell proliferation and beta cell number in RIP-DTA mouse model of beta cell ablation.

References: J Am Chem Soc. 2013 Feb 6; 135(5):1669-72.

Molecular Weight (MW)
568.59
Formula
C29H31F3N6O3
CAS No.
1421227-53-3
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (175.9 mM)
Water: < 1 mg/mL
Ethanol: 100 mg/mL (175.9 mM)
Other info
Chemical Name: 4-[[6-[(cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide
InChi Key: FTODTDQFHDJWIQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C29H31F3N6O3/c1-37-10-12-38(13-11-37)17-21-6-7-22(15-24(21)29(30, 31)32)35-26(39)14-19-2-8-23(9-3-19)41-27-16-25(33-18-34-27)36-28(40)20-4-5-20/h2-3, 6-9, 15-16, 18, 20H, 4-5, 10-14, 17H2, 1H3, (H, 35, 39)(H, 33, 34, 36, 40)
SMILES Code: O=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)CC3=CC=C(OC4=NC=NC(NC(C5CC5)=O)=C4)C=C3
Synonyms
WS-6; WS 6; WS6;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
available

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