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gsk2578215a

gsk2578215a

Item no.	V0775-2mg
Manufacturer	InvivoChem LLC
CASRN	1285515-21-0
Amount	2 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0775CAS #:1285515-21-0Purity >=98% Description: GSK2578215A (GSK-2578215A; GSK 2578215A; GSK-2578215 A) is a novel, highly potent and selective LRRK2 kinase inhibitor with anti-PD (Parkinson's disease) activity. It inhibits LRRK2 (G2019S) and LRRK2 (WT) with an IC50 of 8.9 nM and 10.9 nM, respectively. References: Bioorg Med Chem Lett. 2012 Sep 1; 22(17):5625-9; Cell Death Dis. 2014 Aug 14; 5:e1368.
Molecular Weight (MW)	399.42
Formula	C24H18FN3O2
CAS No.	1285515-21-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 79 mg/mL (197.8 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES	O=C(NC1=CC=CN=C1)C2=CC(C3=CC(F)=NC=C3)=CC=C2OCC4=CC=CC=C4
Synonyms	GSK-2578215A; GSK 2578215A; GSK2578215A; 2-(benzyloxy)-5-(2-fluoropyridin-4-yl)-N-(pyridin-3-yl)benzamide InChi Key: WCIGMFCFPXZRMQ-UHFFFAOYSA-N InChi Code: InChI=1S/C24H18FN3O2/c25-23-14-19(10-12-27-23)18-8-9-22(30-16-17-5-2-1-3-6-17)21(13-18)24(29)28-20-7-4-11-26-15-20/h1-15H, 16H2, (H, 28, 29)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2 mg

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