FH535

Item no.	V0831-1g
Manufacturer	InvivoChem LLC
CASRN	108409-83-2
Amount	1 g
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0831CAS #:108409-83-2Purity >=98% Description: FH535 (FH-535; FH 535) is a novel and potent dual inhibitor of the Wnt/beta-catenin and the PPAR (gamma/delta) pathways with potential antitumor activity. It shows potent anti-proliferative activity in vitro against various cancer cells such as colon, lung, and hepatocellular carcinomas but not normal fibroblasts. FH535 also exhibits excellent in vivo antitumor efficacy in pancreatic cancer xenografts. Description: References: Mol Cancer Ther. 2008; 7(3):521-9; Int J Toxicol. 2012; 31(4):380-9; PLoS One. 2014; 9(6):e99272. References:
Molecular Weight (MW)	361.20
Formula	C13H10Cl2N2O4S
CAS No.	108409-83-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 72 mg/mL (199.3 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES Code	O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O
Synonyms	FH-535; FH535; FH 535; Chemical Name: 2, 5-dichloro-N-(2-methyl-4-nitrophenyl)-benzenesulfonamide InChi Key: AXNUEXXEQGQWPA-UHFFFAOYSA-N InChi Code: InChI=1S/C13H10Cl2N2O4S/c1-8-6-10(17(18)19)3-5-12(8)16-22(20, 21)13-7-9(14)2-4-11(13)15/h2-7, 16H, 1H3 SMILES Code: O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O

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