GW0742

Item no.	V0832-50mg
Manufacturer	InvivoChem LLC
CASRN	317318-84-6
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Cardiovascular Research Ischemia & Reperfusion Injury Hypertension Reagents & Chemicals Arrhythmias Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0832CAS #:317318-84-6Purity >=98% Description: GW0742 (GW-0742; GW 0742; GW-0742X; GW0742X; GW610742; GW-610742) is a potent and highly selective PPARbeta/delta agonist with potential anti-inflammatory activity. It acts by activating PPAR with an IC50 of 1 nM, and exhibits > 1000-fold selectivity for PPARbeta/delta over PPARalpha and PPARgamma. Description: References: Bioorg Med Chem Lett. 2003; 13(9):1517-21; Cell Signal. 2007; 19(6):1163-71; Clin Transl Sci. 2009; 2(2):127-33. References:
Molecular Weight (MW)	471.49
Formula	C21H17F4NO3S2
CAS No.	317318-84-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 94 mg/mL (199.4 mM)
	Water: < 1 mg/mL
	Ethanol: 44 mg/mL (93.3 mM)
Solubility (In vivo)	30% propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL
Synonyms	GW-0742X; GW-610742; GW0742; GW-0742; GW 0742X; GW610742; GW 0742; GW0742X; GW 610742 Chemical Name: [4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid InChi Key: HWVNEWGKWRGSRK-UHFFFAOYSA-N InChi Code: InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23, 24)25/h3-8H, 9-10H2, 1-2H3, (H, 27, 28) SMILES Code: O=C(O)COC1=CC=C(SCC2=C(C)N=C(C3=CC=C(C(F)(F)F)C(F)=C3)S2)C=C1C

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Amount: 50 mg

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Delivery expected until 10/2/2025

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