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Description: Vidofludimus (4SC101; SC-12267; SC12267, 4SC-101; 4SC 101; SC 12267) is a novel, potent and orally bioactive/bioavailable inhibitor of dihydroorotate dehydrogenase (DHODH) with potential anti-inflammatory, immunomodulating and anti-viral activities. In inhibits DHODH with an IC50 of 134 nM for human DHODH.
References: Am J Pathol. 2010 Jun; 176(6):2840-7; J Pharmacol Exp Ther. 2012 Sep; 342(3):850-60.
Related CAS #: 1354023-23-6 (tris); 717824-30-1 (free acid); 2245772-26-1 (sodium); 1354012-90-0 (Calium); 1354013-27-6 (potassium);
Chemical Name: 2-((3-fluoro-3'-methoxy-[1, 1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylic acid
InChi Key: XPRDUGXOWVXZLL-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2, 4-5, 8-11H, 3, 6-7H2, 1H3, (H, 22, 23)(H, 24, 25)
SMILES Code: COC1=CC=CC(C2=CC(F)=C(NC(C3=C(C(O)=O)CCC3)=O)C=C2)=C1
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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