Comparison

Vidofludimus

Item no. V0861-500mg
Manufacturer InvivoChem LLC
CASRN 717824-30-1
Amount 500 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0861CAS #:717824-30-1Purity >=98%

Description: Vidofludimus (4SC101; SC-12267; SC12267, 4SC-101; 4SC 101; SC 12267) is a novel, potent and orally bioactive/bioavailable inhibitor of dihydroorotate dehydrogenase (DHODH) with potential anti-inflammatory, immunomodulating and anti-viral activities. In inhibits DHODH with an IC50 of 134 nM for human DHODH.

Description:

References: Am J Pathol. 2010 Jun; 176(6):2840-7; J Pharmacol Exp Ther. 2012 Sep; 342(3):850-60.

Related CAS #: 1354023-23-6 (tris); 717824-30-1 (free acid); 2245772-26-1 (sodium); 1354012-90-0 (Calium); 1354013-27-6 (potassium);

Molecular Weight (MW)
355.36
Formula
C20H18FNO4
CAS No.
717824-30-1
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (281.4 mM)
Water: < 1 mg/mL
Ethanol: < 1 mg/mL
Solubility (In vivo)

Chemical Name: 2-((3-fluoro-3'-methoxy-[1, 1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylic acid

InChi Key: XPRDUGXOWVXZLL-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2, 4-5, 8-11H, 3, 6-7H2, 1H3, (H, 22, 23)(H, 24, 25)

SMILES Code: COC1=CC=CC(C2=CC(F)=C(NC(C3=C(C(O)=O)CCC3)=O)C=C2)=C1

Synonyms
4SC101; SC-12267; SC12267, 4SC-101; 4SC 101; SC 12267.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

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