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Description: Glycyrrhizic Acid (also known as Glizigen; Liquorice; Glycyrrhizin), a naturally occurring triterpenoid saponin analog found in the licorice root, is a widely used anti-inflammatory agent but also has anticancer activities. Glycyrrhizic acid is responsible for the sweet taste of Glycyrrhiza glabra (liquorice) root. Structurally it is a saponin and has been used as an emulsifier and gel-forming agent in foodstuff and cosmetics. Its aglycone is enoxolone and it has therefore been used as a prodrug for that compound, for example it is used in Japan to prevent liver carcinogenesis in patients with chronic hepatitis C.
References: J Steroid Biochem Mol Biol. 2002 Apr; 80(4-5):441-7.
Related CAS #: 1407-03-0 (Ammonium Glycyrrhizinate); 1405-86-3 (Glycyrrhizic acid)
Chemical Name: (2S, 3S, 4S, 5R, 6R)-6-(((2S, 3R, 4S, 5S, 6S)-6-carboxy-2-(((3R, 4aR, 6aR, 6bS, 8aS, 11R, 12aR, 14aR, 14bS)-11-carboxy-4, 4, 6a, 6b, 8a, 11, 14b-heptamethyl-14-oxo-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicen-3-yl)oxy)-4, 5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3, 4, 5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChi Key: LPLVUJXQOOQHMX-ACOLGLFUSA-N
InChi Code: InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4, 36(53)54)13-12-38(19, 3)14-15-41(18, 42)6)40(21, 5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16, 19, 21-31, 34-35, 44-48H, 8-15, 17H2, 1-7H3, (H, 49, 50)(H, 51, 52)(H, 53, 54)/t19-, 21-, 22+, 23-, 24-, 25-, 26-, 27+, 28-, 29-, 30+, 31+, 34-, 35-, 38+, 39+, 40-, 41+, 42+/m0/s1
SMILES Code: O[CH]([CH]([CH](C(O)=O)O1)O)[CH](O[CH]2[CH]([CH]([CH]([CH](C(O)=O)O2)O)O)O)[CH]1O[CH](C(C)([C](CC[C]([C]3(CC[C]4(CC[C](C[C]4(C3=C5)[H])(C(O)=O)C)C)C)6C)7[H])C)CC[C]7(C)[C]6([H])C5=O
Glizigen; Liquorice; Glycyrrhizin;
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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