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VER-50589

VER-50589

Item no.	V0882-100mg
Manufacturer	InvivoChem LLC
CASRN	747413-08-7
Amount	100 mg
Quantity options	10 mg 1 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Cardiovascular Research Thrombosis & Hemostasis Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0882CAS #:747413-08-7Purity >=98% Description: VER-50589 (VER 50589; VER50589) is a highly potent and selective HSP90 (Heat Shock Protein 90) inhibitor with potential antineoplastic activity. It inhibits HSP90 with an IC50 of 21 nM for HSP90beta. VER-50589 exhibits excellent anti-proliferative activity in vitro with a mean cellular antiproliferative GI50 of 78 nM against a human cancer cell lines. It also demonstrates high in vivo antitumor efficacy in HCT116 human colon cancer xenografts. Description:HCT116 human colon cancer xenografts. References: Mol Cancer Ther. 2007 Apr; 6(4):1198-211. References:
Molecular Weight (MW)	388.80
Formula	C19H17ClN2O5
CAS No.	747413-08-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 77 mg/mL (198.0 mM)
	Water: < 1 mg/mL
	Ethanol: 77 mg/mL (198.0 mM)
Other info	Chemical Name: 5-(5-chloro-2, 4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)isoxazole-3-carboxamide InChi Key: JXPCDMPJCKNLBY-UHFFFAOYSA-N InChi Code: InChI=1S/C19H17ClN2O5/c1-3-21-19(25)17-16(10-4-6-11(26-2)7-5-10)18(27-22-17)12-8-13(20)15(24)9-14(12)23/h4-9, 23-24H, 3H2, 1-2H3, (H, 21, 25) SMILES Code: O=C(C1=NOC(C2=CC(Cl)=C(O)C=C2O)=C1C3=CC=C(OC)C=C3)NCC
Synonyms	VER 50589; VER-50589; VER50589;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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