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Phenoxybenzamine HCl

Phenoxybenzamine HCl

Item no.	V1145-5g
Manufacturer	InvivoChem LLC
CASRN	63-92-3
Amount	5 g
Quantity options	10 g 1 g 250 mg 2 g 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1145CAS #:63-92-3Purity >=98% Description: Phenoxybenzamine HCl (formerly NSC-37448; NSC37448; Dibenzyline, NCI-C01661, NCIC01661; NCI-c01661), the hydrochloride salt of Phenoxybenzamine, is a potent, non-specific, irreversible alpha-adrenergic receptor antagonist with antihypertensive effects. It inhibits alpha-adrenergic receptor with an IC50 of 550 nM. Phenoxybenzamine has been used in the treatment of hypertension, and specifically that caused by pheochromocytoma. It has a slower onset and a longer-lasting effect compared with other a-blockers. It was also the first alpha blocker to be used for treatment of benign prostatic hyperplasia, although it is rarely used today. Description: References: Br J Urol. 1978 Dec; 50(7):551-4 References: Related CAS #: 63-92-3 (HCl) 59-96-1 (free base)
Molecular Weight (MW)	340.3
Formula	C18H22ClNO.HCl
CAS No.	63-92-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 68 mg/mL (199.8 mM)
	Water: 17 mg/mL (50.0 mM)
	Ethanol: 68 mg/mL (199.8 mM)
Other info	Chemical Name: N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine hydrochloride InChi Key: VBCPVIWPDJVHAN-UHFFFAOYSA-N InChi Code: InChI=1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17; /h2-11, 16H, 12-15H2, 1H3; 1H SMILES Code: CC(N(CCCl)CC1=CC=CC=C1)COC2=CC=CC=C2.[H]Cl
Synonyms	NSC-37448; Phenoxybenzamine hydrochloride, NCI C01661, Phenoxybenzamine, Phenoxybenzamine HCl, NSC 37448; NSC37448; Dibenzyline, NCI-C01661, NCIC01661

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Amount: 5 g

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