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IKK-16 HCl

IKK-16 HCl

Item no.	V11748-100mg
Manufacturer	InvivoChem LLC
CASRN	1186195-62-9
Amount	100 mg
Quantity options	10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V11748CAS #:1186195-62-9Purity >=98% Description:IKK-16 HCl (also known as IKK Inhibitor VII) is a novel , potent andselective IkappaBalpha kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1with IC50 of 40 nM, 70 nM and 200 nM in cell-free assays, respectively. In addition, IKK-16 has been found to be active atthioglycollate-induced peritonitis model in the mouse. Furthermore, IKK-16 has revealed to be an orally bio-available in rats and mice, andhave significant in vivo activity in an acute model of cytokine release. References: Bioorg Med Chem Lett. 2006 Jan 1; 16(1):108-12. Related CAS #:873225-46-8 (free base) 1186195-62-9 (HCl) Description:IKK-16 HCl (also known as IKK Inhibitor VII) is a novel , potent andselective IkappaBalpha kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1with IC50 of 40 nM, 70 nM and 200 nM in cell-free assays, respectively. In addition, IKK-16 has been found to be active atthioglycollate-induced peritonitis model in the mouse. Furthermore, IKK-16 has revealed to be an orally bio-available in rats and mice, andhave significant in vivo activity in an acute model of cytokine release. References: Bioorg Med Chem Lett. 2006 Jan 1; 16(1):108-12. Related CAS #:873225-46-8 (free base) 1186195-62-9 (HCl)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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