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Description: Pentoxyverine Citrate (Loucarbate; Carbetapentane Citrate), the citrate salt of Pentoxyverine, is an agonist of the sigma-1 receptor and an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. It is sold over-the-counter/OTC in the United States as Solotuss, or in combination with other medications, especially decongestants. One such product is Certuss, a combination of guaifenesin and pentoxyverine.
References: Talanta. 2011 Feb 15; 83(5):1601-5; Wikipedia
Related CAS: 77-23-6 (free); 23142-01-0 (dihydrogen citrate); 1406-98-0 (tannate)
Chemical Name: 2-[2-(Diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate citrate
InChi Key: AKJDEXBCRLOVTH-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H31NO3.C6H8O7/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18; 7-3(8)1-6(13, 5(11)12)2-4(9)10/h5-7, 10-11H, 3-4, 8-9, 12-17H2, 1-2H3; 13H, 1-2H2, (H, 7, 8)(H, 9, 10)(H, 11, 12)
SMILES Code: O=C(C1(C2=CC=CC=C2)CCCC1)OCCOCCN(CC)CC.OC(C(O)=O)(CC(O)=O)CC(O)=O
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