Comparison

Wogonin

Item no. V1184-25mg
Manufacturer InvivoChem LLC
CASRN 632-85-9
Amount 25 mg
Quantity options 100 mg 10 mg 1 g 250 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V1184CAS #:632-85-9Purity >=98%

Description: Wogonin (Vogonin), a naturally occurring and pharmacologically-active flavonoid found in plants, has been reported to exhibit anticancer effects against various cancer cell types such as osteosarcoma, leukemia, breast cancer and glioma. Wogonin induced a G1 phase cell cycle arrest in HCT116 cells in a concentration- and time-dependent manner. Meanwhile, the cell cycle-related proteins, such as cyclin A, E, D1, and CDK2, 4 were down-regulated in wogonin-induced G1 cell cycle arrest. Furthermore, we showed that the anti-proliferation and G1 arrest effect of wogonin on HCT116 cells was associated with deregulation of Wnt/beta-catenin signaling pathway.

References: Toxicology. 2013 Oct 4; 312:36-47; Neurol Sci. 2015 Jul; 36(7):1181-8.

Related CAS: 51059-44-0 (Wogonoside)

Molecular Weight (MW)
284.26
Formula
C16H12O5
CAS No.
632-85-9
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 56 mg/mL (197.0 mM)
Water: < 1 mg/mL
Ethanol: 8 mg/mL (28.1 mM)
Other info

Chemical Name: 4H-1-Benzopyran-4-one, 5, 7-dihydroxy-8-methoxy-2-phenyl-

InChi Key: XLTFNNCXVBYBSX-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8, 17, 19H, 1H3

SMILES Code: O=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(O)=CC(O)=C13

Synonyms
Vogonin

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
available

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