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ROC-325

ROC-325

Item no.	V13944-250mg
Manufacturer	InvivoChem LLC
CASRN	1859141-26-6
Amount	250 mg
Quantity options	100 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V13944CAS #:1859141-26-6Purity >=98% Description: ROC-325 is a novel, potent and orally bioactive autophagy inhibitor with potent anticancer activity. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC-325 antagonized RCC growth and survival in an ATG5/7-dependent manner, induced apoptosis, and exhibited favorable selectivity. References: Carew JS, Nawrocki ST. Drain the lysosome: Development of the novel orallyavailable autophagy inhibitor ROC-325. Autophagy. 2017 Apr 3; 13(4):765-766. doi:10.1080/15548627.2017.1280222. Epub 2017 Jan 24. PubMed PMID: 28118053.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 9/4/2025

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