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ROC-325

ROC-325

Item no.	V13944-25mg
Manufacturer	InvivoChem LLC
CASRN	1859141-26-6
Amount	25 mg
Quantity options	100 mg 250 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V13944CAS #:1859141-26-6Purity >=98% Description: ROC-325 is a novel, potent and orally bioactive autophagy inhibitor with potent anticancer activity. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC-325 antagonized RCC growth and survival in an ATG5/7-dependent manner, induced apoptosis, and exhibited favorable selectivity. References: Carew JS, Nawrocki ST. Drain the lysosome: Development of the novel orallyavailable autophagy inhibitor ROC-325. Autophagy. 2017 Apr 3; 13(4):765-766. doi:10.1080/15548627.2017.1280222. Epub 2017 Jan 24. PubMed PMID: 28118053.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/4/2025

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