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Aminoglutethimide (BA-16038)

Aminoglutethimide (BA-16038)

Item no.	V1802-1g
Manufacturer	InvivoChem LLC
CASRN	125-84-8
Amount	1 g
Quantity options	100 mg 10 g 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1802CAS #:125-84-8Purity >=98% Description: Aminoglutethimide (also known as BA-16038, NSC-330915) is an an anticancer drug that acts as a nonsteroidal aromatase inhibitor with IC50 of 10 uM. Aminoglutethimide decreases the production of sex hormones such as estrogen in women or testosterone in men, and suppresses the growth of tumors that need sex hormones to grow. Aminoglutethimide blocks the production of steroids derived from cholesterol and is clinically used in the treatment of Cushing's syndrome and metastatic breast cancer. References: Eur J Med Chem. 2009 Oct; 44(10):4121-7; Cancer Res. 1982 Aug; 42(8 Suppl):3353s-3359s. Related CAS#: 23734-88-5 (Aminoglutethimide phosphate); 55511-44-9 (D)-Aminoglutethimide; 57288-03-6 (S)-Aminoglutethimide; 57344-88-4 (R)-Aminoglutethimide tartrate; 62268-19-3 (S)-Aminoglutethimide tartrate
Molecular Weight (MW)	232.28
Formula	C13H16N2O2
CAS No.	125-84-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 20 mg/mL (86.1 mM)
	Water: < 1 mg/mL
	Ethanol: 7 mg/mL (30.1 mM)
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 8 mg/mL
Synonyms	BA-16038; NSC-330915; BA16038; NSC330915; BA 16038; NSC 330915; Ainoglutethimide; Cytadren; Orimeten; Elipten; Aminoglutetimida; Aminoglutethimidum; Ba16038; Cytadren; Prestwick243; CCRIS 7562; CHEBI:2654; Aminoglutethimidum

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