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BMS-378806

BMS-378806

Item no.	V1839-10mg
Manufacturer	InvivoChem LLC
CASRN	357263-13-9
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1839CAS #:357263-13-9Purity >=98% Description: BMS-378806 (also known as BMS 806) is a novel, potent, orally bioavailable small molecule that selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in HIV virus. BMS-378806 inhibits the first step of HIV-1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It binds the exterior envelope glycoprotein gp120, which can block the conformational change that occurs with CD4 binding and preventing fusion of the viral and target cell membranes. References: J Med Chem. 2003 Sep 25; 46(20):4236-9; Biopharm Drug Dispos. 2005 Dec; 26(9):387-402.
Molecular Weight (MW)	406.43
Formula	C22H22N4O4
CAS No.	357263-13-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 81 mg/mL (199.3 mM)
	Water:< 1 mg/mL
	Ethanol: 3 mg/mL (7.4 mM)
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% Propylene glycol: 30 mg/mL
Synonyms	BMS-806; BMS806; BMS 806; BMS-378806; BMS 378806; BMS378806;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 10/2/2025

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