Comparison

GBR 12935

Item no. V2046-50mg
Manufacturer InvivoChem LLC
CASRN 76778-22-8
Amount 50 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V2046CAS #:76778-22-8 Purity >=98%

Description: GBR-12935 is a novel, potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain.

References: Eur J Pharmacol. 2001 Feb 23; 414(1):37-44.; Biochem Pharmacol. 1997 Jun 15; 53(12):1937-9.

Related CAS#: 67469-81-2 (HCl); 76778-22-8 (free base)

GBR 12935
Name: GBR-12935
CAS#: 76778-22-8 (free base)
Chemical Formula: C28H34N2O
Exact Mass: 414.2671
Molecular Weight: 414.593
Elemental Analysis: C, 81.12; H, 8.27; N, 6.76; O, 3.86
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: GBR-12935; GBR 12935; GBR12935.
Chemical Name: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine
InChi Key: RAQPOZGWANIDQT-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9, 11-12, 14-17, 28H, 10, 13, 18-24H2
SMILES Code: N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(CCCC4=CC=CC=C4)CC1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
available

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