GNF179

Item no.	V2122-25mg
Manufacturer	InvivoChem LLC
CASRN	1261114-01-5
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2122CAS #:1261114-01-5Purity >=98% Description: GNF179, an optimized 8, 8-dimethyl imidazolopiperazine analog, is a novel, potent and orally bioavailable antiparasitic agent that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability. Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic forms would be preferable. References: Science. 2011 Dec 9; 334(6061):1372-7. Related CAS#: 1310455-86-7 (GNF179 metabolite)
	Name: GNF179 CAS#: 1261114-01-5 Chemical Formula: C22H23ClFN5O Exact Mass: 427.1575 Molecular Weight: 427.9084 Elemental Analysis: C, 61.75; H, 5.42; Cl, 8.28; F, 4.44; N, 16.37; O, 3.74
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: GNF179; GNF-179; GNF 179 Chemical Name: 2-amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8, 8-dimethyl-5, 6-dihydroimidazo[1, 2-a]pyrazin-7(8H)-yl)ethanone InChi Key: KFSKTWYDIHJITF-UHFFFAOYSA-N InChi Code: InChI=1S/C22H23ClFN5O/c1-22(2)21-27-19(14-3-7-16(24)8-4-14)20(26-17-9-5-15(23)6-10-17)28(21)11-12-29(22)18(30)13-25/h3-10, 26H, 11-13, 25H2, 1-2H3 SMILES Code: CC1(C)C2=NC(C3=CC=C(F)C=C3)=C(NC4=CC=C(Cl)C=C4)N2CCN1C(CN)=O

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Amount: 25 mg

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Delivery expected until 9/4/2025

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