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Olsalazine Sodium (CJ-91B)

Item no. V2451-200g
Manufacturer InvivoChem LLC
CASRN 6054-98-4
Amount 200 g
Quantity options 100 g 10 g 25 g 50 g 5 g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V2451CAS #:6054-98-4 Purity >=98%

Description: Olsalazine Sodium (CJ-91B) is a potent anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.Olsalazine displays multiple effects on intestinal electrolyte. In vitro application of Olsalazine (< 2.89 mM) increases the secretion of both sodium and chloride ions and decreases chloride ion absorption in rat and rabbit ileal mucosa. Concentration of Olsalazine < 11.5 mM also dose-dependently decreases net sodium and, to a greater degree, chloride absorption in the isolated rat colon. Potassium secretion is also increases but only at a high Olsalazine concentration (11.5 mM).

References: 1991 Apr; 41(4):647-64.

Related CAS #: 15722-48-2 (free acid) 6054-98-4 (sodium)

Molecular Weight (MW)
346.2
Formula
C14H8N2O6.2Na
CAS No.
6054-98-4
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 41 mg/mL (118.42 mM)
Water: < 1 mg/mL
Ethanol: 4 mg/mL (11.55 mM)
Other info

Chemical Name: sodium (E)-5, 5'-(diazene-1, 2-diyl)bis(2-hydroxybenzoate)

InChi Key: ZJEFYLVGGFISGT-VRZXRVJBSA-L

InChi Code: InChI=1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22; ; /h1-6, 17-18H, (H, 19, 20)(H, 21, 22); ; /q; 2*+1/p-2/b16-15+; ;

SMILES Code: O=C([O-])C1=C(O)C=CC(/N=N/C2=CC(C([O-])=O)=C(O)C=C2)=C1.[Na+].[Na+]

Synonyms
CJ-91B; CJ 91B; CJ91B; Olsalazine, Dipentum, Azodisal sodium, Azodisalicylate

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 g
Available: In stock
available

Delivery expected until 9/4/2025 

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