« Back
Home /
MM-12 TFA

MM-12 TFA

Item no.	V32086-50mg
Manufacturer	InvivoChem LLC
CASRN	1883545-52-5
Amount	50 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #: V32086 CAS #: 1883545-52-5 Purity >=98% Description: MM-102 TFA (the trifluoroacetic acid salt of MM-102) is a novel, potent, high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 uM in a cell-free assay. MM-102 reduces the expression of MLL1 targeted genes HoxA9 and Meis-1 in MLL1-AF9 transduced murine cells. Since these two genes are required for MLL1 mediated leukemogenesis, MM-102 is found to inhibit cell growth of leukemia cells harboring MLL1 fusion proteins. It dose-dependently inhibits the cell growth in the MV4; 11 and KOPN8 cell lines with IC50 values both of 25uM. References: J Am Chem Soc. 2013 Jan 16; 135(2):669-82. Related CAS: 1417329-24-8 (free base)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 mg

available

Delivery expected until 2/5/2026

Express Delivery: Save 22 days

Compare

Add to wishlist

Get an offer