« Back
Home /
kb-NB77-78

kb-NB77-78

Item no.	V3423-100mg
Manufacturer	InvivoChem LLC
CASRN	1350622-33-1
Amount	100 mg
Quantity options	10 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3423CAS #:1350622-33-1 Purity >=98% Description: kb-NB77-78 is a CID797718 analog but without PKD (Protein kinase D) inhibitory activity. Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specific inhibitor. The benzoxoloazepinolone CID755673 was recently reported as the first potent and kinase-selective inhibitor for this enzyme. For structure-activity analysis purposes, a series of analogs was prepared and their in vitro inhibitory potency evaluated. References: Pharmaceutics. 2011; 3(2):186-228.
	Name: kb-NB77-78 CAS#: 1350622-33-1 Chemical Formula: C18H25NO3Si Exact Mass: 331.1604 Molecular Weight: 331.48 Elemental Analysis: C, 65.22; H, 7.60; N, 4.23; O, 14.48; Si, 8.47
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Kb-NB77-78; KbNB7778; Kb NB77 78 Chemical Name: 9-((tert-butyldimethylsilyl)oxy)-1, 2, 3, 4-tetrahydro-5H-chromeno[3, 4-b]pyridin-5-one InChi Key: UNMWMPXUIXEQJZ-UHFFFAOYSA-N InChi Code: InChI=1S/C18H25NO3Si/c1-18(2, 3)23(4, 5)22-12-8-9-15-14(11-12)13-7-6-10-19-16(13)17(20)21-15/h8-9, 11, 19H, 6-7, 10H2, 1-5H3 SMILES Code: O=C(C1=C2CCCN1)OC3=C2C=C(O[Si](C)(C(C)(C)C)C)C=C31

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer