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GSK484 free base

GSK484 free base

Item no.	V36344-25mg
Manufacturer	InvivoChem LLC
CASRN	1652629-23-6
Amount	25 mg
Quantity options	100 mg 10 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V36344CAS #:1652591-81-5Purity >=98% Description: GSK484 HCl is a novel, potent, selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor which showes high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. References: 1. LewisHD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouseand human NET formation. Nat Chem Biol. 2015 Mar; 11(3):189-91. 2. CedervallJ, et al. Pharmacological targeting of peptidylarginine deiminase 4prevents cancer-associated kidney injury in mice. Oncoimmunology. 2017Apr 20; 6(8):e1320009. Related CAS #: 1652629-23-6 (free base) 1652591-81-5 (HCl)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 7/3/2025

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