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PDD00017273

PDD00017273

Item no.	V40907-10mg
Manufacturer	InvivoChem LLC
CASRN	1945950-21-9
Amount	10 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V40907CAS #:1945950-21-9Purity >=98% Description: PDD00017273 is a novel, potent andselective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50of 26 nM. PDD00017273 exhibits > 350-fold selectivity for PARG over apanel of ion channels, enzymes and receptors, including PARP1 andARH3. References: 1. JamesDI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose)Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacologyto AZD2281. ACS Chem Biol. 2016 Nov 18; 11(11):3179-3190. Epub 2016 Oct12. 2. GravellsP, et al. Specific killing of DNA damage-response deficient cells withinhibitors of poly(ADP-ribose) glycohydrolase. DNA Repair (Amst). 2017Apr; 52:81-91.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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