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pdd00017273

pdd00017273

Item no.	V40907-25mg
Manufacturer	InvivoChem LLC
CASRN	1945950-21-9
Amount	25 mg
Quantity options	100 mg 10 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V40907CAS #:1945950-21-9Purity >=98% Description: PDD00017273 is a novel, potent andselective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50of 26 nM. PDD00017273 exhibits > 350-fold selectivity for PARG over apanel of ion channels, enzymes and receptors, including PARP1 andARH3. References: 1. JamesDI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose)Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacologyto AZD2281. ACS Chem Biol. 2016 Nov 18; 11(11):3179-3190. Epub 2016 Oct12. 2. GravellsP, et al. Specific killing of DNA damage-response deficient cells withinhibitors of poly(ADP-ribose) glycohydrolase. DNA Repair (Amst). 2017Apr; 52:81-91.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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