Comparison

arzoxifene-hcl

Item no. V4903-250mg
Manufacturer InvivoChem LLC
CASRN 182133-27-3
Amount 250 mg
Quantity options 100 mg 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V4903CAS #:182133-27-3 (HCl)Purity >=98%

Description: Arzoxifene (also known as LY353381) is a novel, potent, synthetic aromatic derivative, and selective estrogen receptor antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol. Arzoxifene binds to estrogen receptors as a mixed estrogen agonist/antagonist. In comparison to other selective estrogen receptor modulators (SERMs), arzoxifene exhibits greater bioavailability and higher anti-estrogenic potency in the breast than raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. This agent may have beneficial effects on bone and the cardiovascular system.

References: Cancer Res. 2001 Dec 1; 61(23):8412-5.

Related CAS : 153559-76-3 (LG100268); 63676-25-5 (LY 117018)

Arzoxifene HCl

Name: Arzoxifene hydrochloride
CAS#: 182133-27-3 (HCl)
Chemical Formula: C28H30ClNO4S
Exact Mass:
Molecular Weight: 512.06
Elemental Analysis: C, 65.68; H, 5.91; Cl, 6.92; N, 2.74; O, 12.50; S, 6.26
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: LY353381 HCl; LY353381; LY-353381; LY 353381; SERM3; Arzoxifene HCl; Arzoxifene hydrochloride.
IUPAC/Chemical Name: 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol , hydrochloride
InChi Key: NHSNLUIMAQQXGR-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H29NO4S.ClH/c1-31-22-8-5-20(6-9-22)28-27(25-14-7-21(30)19-26(25)34-28)33-24-12-10-23(11-13-24)32-18-17-29-15-3-2-4-16-29; /h5-14, 19, 30H, 2-4, 15-18H2, 1H3; 1H
SMILES Code: OC1=CC=C2C(OC3=CC=C(OCCN4CCCCC4)C=C3)=C(C5=CC=C(OC)C=C5)SC2=C1.[H]Cl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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