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arzoxifene-hcl

arzoxifene-hcl

Item no.	V4903-25mg
Manufacturer	InvivoChem LLC
CASRN	182133-27-3
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 250 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4903CAS #:182133-27-3 (HCl)Purity >=98% Description: Arzoxifene (also known as LY353381) is a novel, potent, synthetic aromatic derivative, and selective estrogen receptor antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol. Arzoxifene binds to estrogen receptors as a mixed estrogen agonist/antagonist. In comparison to other selective estrogen receptor modulators (SERMs), arzoxifene exhibits greater bioavailability and higher anti-estrogenic potency in the breast than raloxifene; it exhibits reduced estrogenicity in the uterus compared with either tamoxifen or raloxifene. This agent may have beneficial effects on bone and the cardiovascular system. References: Cancer Res. 2001 Dec 1; 61(23):8412-5. Related CAS : 153559-76-3 (LG100268); 63676-25-5 (LY 117018)
	Name: Arzoxifene hydrochloride CAS#: 182133-27-3 (HCl) Chemical Formula: C28H30ClNO4S Exact Mass: Molecular Weight: 512.06 Elemental Analysis: C, 65.68; H, 5.91; Cl, 6.92; N, 2.74; O, 12.50; S, 6.26
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: LY353381 HCl; LY353381; LY-353381; LY 353381; SERM3; Arzoxifene HCl; Arzoxifene hydrochloride. IUPAC/Chemical Name: 2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol , hydrochloride InChi Key: NHSNLUIMAQQXGR-UHFFFAOYSA-N InChi Code: InChI=1S/C28H29NO4S.ClH/c1-31-22-8-5-20(6-9-22)28-27(25-14-7-21(30)19-26(25)34-28)33-24-12-10-23(11-13-24)32-18-17-29-15-3-2-4-16-29; /h5-14, 19, 30H, 2-4, 15-18H2, 1H3; 1H SMILES Code: OC1=CC=C2C(OC3=CC=C(OCCN4CCCCC4)C=C3)=C(C5=CC=C(OC)C=C5)SC2=C1.[H]Cl

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Amount: 25 mg

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Delivery expected until 9/4/2025

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