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GW-7647

GW-7647

Item no.	V4928-100mg
Manufacturer	InvivoChem LLC
CASRN	265129-71-3
Amount	100 mg
Quantity options	250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4928CAS #:265129-71-3Purity >=98% Description: GW7647 (GW-7647) is a novel, selective and potent agonist of human and murine PPARalpha4 with EC50s of 6 nM, 1.1 uM, and 6.2 uM for human PPARalpha, PPARgamma and PPARdelta, respectively. It was discovered using solid-phase, parallel-array synthesis and assayed for activity on the human PPAR subtypes. GW7647 was identified as a potent human PPARalpha agonist with approximately 200-fold selectivity over PPARgamma and PPARdelta, and potent lipid-lowering activity in animal models of dyslipidemia. GW7647 will be a valuable chemical tool for studying the biology of PPARalpha in human cells and animal models of disease. References: Bioorg Med Chem Lett. 2001 May 7; 11(9):1225-7.
	Name: GW-7647 CAS#: 265129-71-3 Chemical Formula: C29H46N2O3S Exact Mass: 502.3229 Molecular Weight: 502.758 Elemental Analysis: C, 69.28; H, 9.22; N, 5.57; O, 9.55; S, 6.38
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: GW-7647; GW 7647; GW7647. IUPAC/Chemical Name: 2-((4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)ethyl)phenyl)thio)-2-methylpropanoic acid InChi Key: PKNYXWMTHFMHKD-UHFFFAOYSA-N InChi Code: InChI=1S/C29H46N2O3S/c1-29(2, 27(32)33)35-26-18-16-24(17-19-26)20-22-31(28(34)30-25-14-7-4-8-15-25)21-10-9-13-23-11-5-3-6-12-23/h16-19, 23, 25H, 3-15, 20-22H2, 1-2H3, (H, 30, 34)(H, 32, 33) SMILES Code: CC(C)(SC1=CC=C(CCN(C(NC2CCCCC2)=O)CCCCC3CCCCC3)C=C1)C(O)=O

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Amount: 100 mg

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Delivery expected until 11/6/2025

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