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NSC23925 HCl

NSC23925 HCl

Item no.	V5031-250mg
Manufacturer	InvivoChem LLC
CASRN	858474-14-3
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5031CAS #:858474-14-3Purity >=98% Description: NSC23925 is a novel, potent, selective and effective P-glycoprotein (Pgp) inhibitor that is able to reverse multidrug resistance (MDR), e.g. it prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis. NSC23925 can prevent the emergence of MDR in ovarian cancer both in vitro and in vivo. The clinical use of NSC2395 at the onset of chemotherapy may prevent the development of MDR and improve the clinical outcome of patients with ovarian cancer. References: Int J Cancer. 2015 Oct 15; 137(8):2029-39.; PLoS One. 2009 Oct 12; 4(10):e7415.
	Name: NSC23925 CAS#: 858474-14-3 Chemical Formula: C22H26Cl2N2O2 Exact Mass: 420.14 Molecular Weight: 421.36 Elemental Analysis: C, 62.71; H, 6.22; Cl, 16.83; N, 6.65; O, 7.59
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: NSC23925; NSC-23925; NSC 23925; NSC 23925 HCl IUPAC/Chemical Name: 2-(p-Methoxyphenyl)-alpha-2-piperidyl-4-quinolinemethanol Dihydrochloride InChi Key: WGWOQHWZXLGPNG-UHFFFAOYSA-N InChi Code: InChI=1S/C22H24N2O2.2ClH/c1-26-16-11-9-15(10-12-16)21-14-18(17-6-2-3-7-19(17)24-21)22(25)20-8-4-5-13-23-20; ; /h2-3, 6-7, 9-12, 14, 20, 22-23, 25H, 4-5, 8, 13H2, 1H3; 2*1H SMILES Code: OC(C1NCCCC1)C2=CC(C3=CC=C(OC)C=C3)=NC4=CC=CC=C24.[H]Cl.[H]Cl

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 9/4/2025

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