Comparison

PLX-647

Item no. V5141-50mg
Manufacturer InvivoChem LLC
CASRN 873786-09-5
Amount 50 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #: V5141
CAS #: 873786-09-5
Purity >=98%



Description: PLX-647 is a novel, potent and highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively. PLX647 shows strong selectivity compared with other kinases. PLX647 represents a unique class of kinase inhibitors with unique dual FMS and KIT specificity.

References: Proc Natl Acad Sci U S A. 2013 Apr 2; 110(14):5689-94.

Related CAS #: 873786-09-5 (PLX-647?; 923562-22-5 PLX647(OMe)
PLX-647
Name: PLX-647
CAS#: 873786-09-5
Chemical Formula: C21H17F3N4
Exact Mass: 382.14053
Molecular Weight: 382.38
Elemental Analysis: C, 65.96; H, 4.48; F, 14.91; N, 14.65
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: PLX647; PLX 647; PLX-647.
Chemical Name: 5-((1H-pyrrolo[2, 3-b]pyridin-3-yl)methyl)-N-(4-(trifluoromethyl)benzyl)pyridin-2-amine
InChi Key: NODCQQSEMCESEC-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H17F3N4/c22-21(23, 24)17-6-3-14(4-7-17)11-26-19-8-5-15(12-27-19)10-16-13-28-20-18(16)2-1-9-25-20/h1-9, 12-13H, 10-11H2, (H, 25, 28)(H, 26, 27)
SMILES Code: FC(C1=CC=C(C=C1)CNC2=NC=C(CC3=CNC4=NC=CC=C43)C=C2)(F)F

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
available

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