« Back
Home /
BTK inhibitor 27

BTK inhibitor 27

Item no.	V5248-100mg
Manufacturer	InvivoChem LLC
CASRN	2230724-66-8
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5248CAS #:2230724-66-8Purity >=98% Description: BTK inhibitor 27, compound 27 in the cited reference below, is a pyrrolo2, 3-dpyrimidine based BTK inhibitor with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. Btk is a tyrosine kinase dysregulated in several B-cell malignancies and autoimmune diseases, and this has given rise to a search for Btk inhibitors. Nevertheless, only one Btk inhibitor, ibrutinib, has been approved to date, although other compounds are currently being evaluated in clinical trials or in preclinal stages. References: Expert Opin Ther Pat. 2017 Dec; 27(12):1305-1318.
	CAS Number: 2230724-66-8 Molecular Weight: 474.49 Molecular Formula: C24H23FN8O2O
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	BTK inhibitor 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer