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BTK inhibitor 27

BTK inhibitor 27

Item no.	V5248-10mg
Manufacturer	InvivoChem LLC
CASRN	2230724-66-8
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5248CAS #:2230724-66-8Purity >=98% Description: BTK inhibitor 27, compound 27 in the cited reference below, is a pyrrolo2, 3-dpyrimidine based BTK inhibitor with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. Btk is a tyrosine kinase dysregulated in several B-cell malignancies and autoimmune diseases, and this has given rise to a search for Btk inhibitors. Nevertheless, only one Btk inhibitor, ibrutinib, has been approved to date, although other compounds are currently being evaluated in clinical trials or in preclinal stages. References: Expert Opin Ther Pat. 2017 Dec; 27(12):1305-1318.
	CAS Number: 2230724-66-8 Molecular Weight: 474.49 Molecular Formula: C24H23FN8O2O
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	BTK inhibitor 1

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Amount: 10 mg

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