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Bitopertin (RG-1678; RO-4917838)

Bitopertin (RG-1678; RO-4917838)

Item no.	V7169-50mg
Manufacturer	InvivoChem LLC
CASRN	845614-11-1
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V7169CAS #:845614-11-1Purity >=98% Description: Bitopertin (Paliflutine, RG1678; RO4917838) is a novel, potent and non-competitive glycine reuptake inhibitor against human GlyT1 with IC50 of 25 nM. It is under development as an adjunct to antipsychotics for the treatment of persistent negative symptoms or suboptimally-controlled positive symptoms associated with schizophrenia. Bitopertin-mediated glycine reuptake inhibition may represent a novel treatment option for schizophrenia, with the potential to address negative symptoms. References: Neuropharmacology. 2012 Feb; 62(2):1152-61.; J Med Chem . 2010 Jun 24; 53(12):4603-14.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 9/4/2025

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