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Chromeceptin

Chromeceptin

Item no.	HY-115449-5mg
Manufacturer	MedChem Express
CASRN	331859-86-0
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.80
Formula	C19H16F3N3O
Citations	[1]Seol HS, et al. Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma. Sci Rep. 2020 Dec 8;10(1):21412.
Smiles	N#CC1=C(N)OC2=CC(N(C)C)=CC=C2C1C3=CC=CC(C(F)(F)F)=C3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	94G6
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Akt; IGF-1R; mTOR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	359.35
Product Description	Chromeceptin (94G6) is an IGF signaling pathway inhibitor. Chromeceptin suppresses IGF2 expression at mRNA and protein levels in hepatocyte and HCC cells. Chromeceptin inhibits the phosphorylation levels of AKT and mTOR[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Clinical information	No Development Reported

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HY-115449-5mg-safety-datasheet.pdf