RSC133

Item no.	HY-12310-1ea
Manufacturer	MedChem Express
CASRN	1418131-46-0
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.0
Citations	[1]Lee J, et al. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12509-13.
Smiles	NC(C1=CC=CC(NC(/C=C/C2=CNC3=CC=CC=C23)=O)=C1)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Methyltransferase; HDAC
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	305.33
Product Description	RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1].
Manufacturer - Research Area	Others
Solubility	DMSO : 20 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Epigenetics
Clinical information	No Development Reported

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