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2-Chlorohexadecanoic acid

2-Chlorohexadecanoic acid

Item no.	HY-131688-1ea
Manufacturer	MedChem Express
CASRN	19117-92-1
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.88
Citations	[1]Eva Bernhart, et al. 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells. Redox Biol. 2018 May;15:441-451.
Smiles	CCCCCCCCCCCCCCC(Cl)C(O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Caspase; PARP
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	290.87
Product Description	2-Chlorohexadecanoic acid, an inflammatory lipid mediator, interferes with protein palmitoylation, induces ER-stress markers, reduced the ER ATP content, and activates transcription and secretion of IL-6 as well as IL-8.2-Chlorohexadecanoic acid disrupts the mitochondrial membrane potential and induces procaspase-3 and PARP cleavage.2-Chlorohexadecanoic acid can across blood-brain barrier (BBB) and compromises ER- and mitochondrial functions in the human brain endothelial cell line hCMEC/D3[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 20 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Clinical information	No Development Reported

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HY-131688-1ea-safety-datasheet.pdf