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(S)-Navlimetostat

(S)-Navlimetostat

Item no.	HY-139611B-1mg
Manufacturer	MedChem Express
CASRN	2630904-44-6
Amount	1 mg
Quantity options	10 mg 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	97.07
Citations	[1]Thomas P. BOBINSKI, et al. Mta-cooperative prmt5 inhibitors. WO2021050915A1.
Smiles	FC1=C(C=C(C(C#N)=[C@@]1[C@@]2=C(C3=CC=C4C(C(CN)=NNC4=O)=C3)C=NN2C)OC5CC5)Cl
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	(S)-MRTX-1719
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Histone Methyltransferase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	464.88
Product Description	(S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Epigenetics
Isoform	PRMT5
Clinical information	No Development Reported

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HY-139611B-1mg-safety-datasheet.pdf