Comparison

LEB-03-153 European Partner

Item no. HY-143343-1ea
Manufacturer MedChem Express
CASRN 2858812-88-9
Amount 1 ea
Quantity options 100 mg 1 ea
Category
Type Chemicals
Specific against other
Formula C40H44N10O6
Citations [1]Henning NJ, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022 Apr;18(4):412-421.
Smiles C=CCN1C(C2=C(N1C3=NC(C(C)(O)C)=CC=C3)N=C(N=C2)NC4=CC=C(C=C4)N5CCN(CC5)C(CCC6=CC=C(O6)N7CCN(CC7=O)C(C=C)=O)=O)=O
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Available
Product Description
LEB-03-153 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through no linker[1].
Shipping
Room temperature
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
760.84
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer
Solubility
10 mM in DMSO
Target
Wee1
Manufacturers Target
Wee1
Manufacturers Pathway
Cell Cycle/DNA Damage
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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