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VEGFR2-IN-1

VEGFR2-IN-1

Item no.	HY-145849-1ea
Manufacturer	MedChem Express
CASRN	2765224-55-1
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Nafie MS, Boraei ATA. Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer. Bioorg Chem. 2022; 122:105708.
Smiles	C=CCSC1=NN=C(N1/N=C/C2=CNC3=CC=CC=C23)C4=CC5=CC=CC=C5N4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	VEGFR
Shipping Temperature	Room temperature
Molecular Weight	398.48
Product Description	VEGFR2-IN-1 is a potent and selective VEGFR2 inhibitor (IC50=19.8 nM). VEGFR2-IN-1 inhibits cell proliferation and migration through apoptosis activation and VEGFR2 inhibition[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Isoform	VEGFR2/KDR/Flk-1
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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